Plain Language Summary: Advances in hemophilia treatment have greatly increased life expectancy, allowing many people with hemophilia to reach older age. As a result, they are now experiencing age-related health issues such as cardiovascular disease, kidney disease, cancer, osteoporosis, and frailty. This review highlights the need for preventive care, access to primary care providers, and a multidisciplinary approach to help manage both hemophilia and the health challenges that come with aging. Hemophilia treatment centers can play an important role in ensuring patients receive coordinated, lifelong care.
