Mohsenian S, Palla R, Menegatti M, Cairo A, Siboni SM, Neerman-Arbez M, Karimi M, Pargantou H, Asselta R, Mikovic D, Saracevic M, Laros-van Gorkom B, Jacobs L, Shapiro A, Williamson A, Makris M, Casini A, Peyvandi F
Plain Language Summary:
Women and girls with congenital fibrinogen deficiencies face a higher risk of heavy menstrual bleeding and pregnancy-related complications than the general population. In a study of 59 women, rates of miscarriage and postpartum hemorrhage were notably elevated, even among some women who had few or no symptoms before pregnancy. The findings highlight the importance of early diagnosis, careful monitoring during pregnancy, and preventive treatment strategies when appropriate.
