Relationship between sociodemographic characteristics at presentation and outcomes of provoked venous thromboembolism in United States children: a secondary analysis of the multinational Kids-duration of therapy for thrombosis trial

Wilson HP, Alleyne MM, Ahuja S, Amankwah E, Bruce A, Carpenter SL, Corrales-Medina FF, Mullen CA, Panigrahi A, Srivaths L, Thornburg CD, Verma A, Woods G, Goldenberg NA, Rajpurkar M

This study examined children and teens who experienced venous thromboembolism (VTE), a condition involving blood clots in the veins. Researchers found that clot location differed by age, with teenagers more likely to develop upper-extremity clots and to experience post-thrombotic syndrome, a long-term complication that can cause pain and swelling. The findings suggest that older children and teens may benefit from closer monitoring after treatment and that future studies should better evaluate how social and economic factors influence blood clot outcomes in children.

child; social determinants of health; thrombosis; venous insufficiency; venous thromboembolism.