Innovative Hematology, Inc.

Research Publications

Acquired factor V inhibitor in a case of pediatric venous thrombosis

Contributor(s):

Gupta S, Bunce MW, Cid EA, Camire RM, Shapiro AD

Plain Language Summary:

Researchers reported the first known pediatric case of a blood clot occurring alongside acquired factor V inhibitor, a rare condition that can affect normal blood clotting. A 13-year-old girl with Crohn’s disease developed extensive deep vein thrombosis and was treated successfully with anticoagulation therapy. The clot resolved, the inhibitor disappeared within five months, and her clotting factor levels returned to normal, demonstrating a positive outcome despite this unusual and complex condition.

Keywords:

acquired FV inhibitor, anticoagulation, direct oral anticoagulants, factor V activity, thrombosis